Chiral Analyses of Pollutants by Capillary Electrophoresis
نویسندگان
چکیده
The determination of enantiomeric composition of chiral xenobiotics and pollutants is a very difficult job due to their low amounts and poor detection by commonly used UV detector. But this sort of analysis is an important issue from the health point of view. The chiral analyses of these notorious pollutants by capillary electrophoresis have been discussed in this article. This review discusses the new trends and advancements, which have been achieved in the analyses of chiral pollutants using capillary electrophoresis and the state-of-art of their enaniomeric resolution. This article focuses on sample treatment, applications, optimization, detection, mechanisms of chiral resolution and future perspectives of CE in chiral resolution of xenobiotics. Besides, efforts have also been made to suggest the improvement in CE machine to make it ideal for the analyses of chiral xenobiotics at trace levels.
منابع مشابه
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A common approach in resolving enantiomers of chiral basic drugs by capillary electrophoresis (CE) is to use cyclodextrins (especially their anionic derivatives) as chiral selector in the acidic buffer (pH ≤ 3) in normal or reversed (carrier) mode. Then, some organic modifiers are added to the buffer solution if the resolution is not satisfactory. In case of cetirizine (CTN), applying the same ...
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تاریخ انتشار 2010